Important Israel discovery to help fertility



Important discovery by Israeli researchers may be lined women with fertility problems, and increase their chances of getting pregnant using hormonal fertility treatments. The researchers were able to detect a protein involved in the process dwindling pool of eggs and ovarian aging in women.

According to the researchers, the discovery could lead to treatment to neutralize the activity of the protein, slowing down the process of destruction of eggs and thereby increase the chances of women getting pregnant and giving birth. “This is a substantial segment of the population relevant to women today do not respond well enough to hormonal therapy,” said Professor Ruth Snow, Tel Aviv University.

The study, published last month in the journal PNAS, was held at the Tel Hashomer Hospital and Tel Aviv University, as part of a doctoral dissertation by Dr. Uri-Blfolsky songs. Research team included, among others, Dr. Yehuda Kamari, Dror incision and Dr. Aviv that lipid from Sheba, Professor Biology Department snows cellular and developmental Tel Aviv University and Dr. Efrat Eliyahu Mount Sinai medical Center in the United States.
Women in general and female mammals, oocytes are born with a limited pool. Stock eggs gradually wears away with age until complete loss of reproductive capacity, at the age of 50 or so. The mechanism leading to stock depletion ovarian eggs and spend far understood only partially. “We know that a woman is born with a database of about 2 million eggs. Reservoir is decreasing with age,” says Professor Snow.

She says, “The process of loss of eggs is a continuous process that occurs constantly throughout the course of development of the eggs. They are released all the time from the eggs’ fixed ‘body and from that moment they are in a kind of’ pool portable. One of them comes every month to realize, but most of the eggs die on the way . fixed this mechanism, rather extravagant, development and depletion of oocytes “.This also helps people get rid of constipation.

However, according to the study, one of the factors that contribute to mortality of eggs is a protein called interleukin-1 (IL-1) – who belongs to the group of proteins belonging to the innate immune system. The role of the protein is known to help fight off infections and healing tissue damage. At the same time, the protein is also known as a stimulant unrelated infections and is associated with infections among other inflammatory diseases such as rheumatoid arthritis. Ostensibly, there should be an impact on a woman’s reproductive mechanisms.

This relationship was discovered by chance. “We started working on a few years ago the protein framework of research on atherosclerosis and inflammation in the liver. While research conducted in mice, we found the missing mouse interleukin-1 continue to conceive at the mice in the control group did not get pregnant,” says Dr. Kamer. Phenomenon discovered incidentally, became the basis for new research dealing with the influence of interleukin-1 on reproductive mechanisms.

The researchers found that a lack of protein in the mouse causes the ovaries to respond to the hormone whose role is to induce ovulation. The study examined mice at an older age – girls 10-12 months (equivalent to age 40 for women), found that the pregnancy rate and the number of offspring of mice that neutralized the activity of the protein, was significantly higher in the control group relative to the mouse.

In addition, it was found that the number of eggs in the ovaries of these mice was higher during the reproductive period. “We do not know exactly what course of action which affects the protein on egg mortality,” says Snow. “When it comes to the chain of biochemical processes, sometimes when you close one door opens another door and not always clear how.

This requires further research. Meanwhile, in the present study we found that the lack of the protein interleukin-1 reduces the mortality of eggs. This means more database ovarian oocytes. Practical level this means disabling the protein may allow the future to raise a lot more eggs for fertilization. ”

According to the chamber, triggers inflammation are part of the innate immune system and are designed to help the body cope with external invaders. However, in recent decades increasingly relies also understand that they have other effects on body systems. “In this context, we know that women who suffer from diseases that accompany arthritis suffer from lower fertility,” he says.

According to the researchers, the study results may improve the treatment of women trying to become pregnant through in vitro fertilization in old age, which is obtained at a weak response to hormones. In most cases, the reason for this is unknown, and their treatment is a medical challenge.

What to eat at night?

It is preferable to eat during the day. Ghrelin hormone secreted from the stomach suggests that. It is released in three waves during the day and communicating to us hungry. These waves are directed us to eat breakfast, lunch and dinner. Excreted overnight low level of ghrelin, suggesting then do not eat. Then a hormone called leptin, is secreted by fat cells, is linked to the feeling of satiety and rather middle of the night as a high-level suggesting that our body is not prepared for eating midnight. Since our body is not prepared to eat at night, you should consume foods that attracted Aicholm short and avoid foods that are digested for several hours as meats, boiled eggs, sausages, beans, onions, cheeses, cooked fish or salted, butter, cabbage, lentils, fatty foods and fried foods. Fat Bmzon- in all its forms, inhibits gastric emptying, thus delaying the food in the digestive tract longer hours.

Shaicholm foods are short-lived: Fruits, vegetables, rice, low-fat milk, yogurt, bread, baked potatoes or cooked ..


Here are some suggestions feast night, after going to sink into a good sleep:

Whole wheat sandwich with cream cheese, and tomato. You can add fresh parsley washed and sold as ready to eat bags. Wipe off with a hot drink. Best to avoid caffeinated beverages such as coffee, cocoa, tea, and cola to those strong, caffeine interferes with their sleep.
Bio yogurt with fresh fruit in it + tablespoon chopped curds are another option.
Fresh vegetable salad made ​​with eggs beside a large nonstick skillet with ½ teaspoon oil + whole wheat bread.
Bio yogurt cup with chopped almonds and pear inside
Quick oatmeal preparation with peach or banana slices or raisins in it.
It is recommended that the meal is not larger. Again- to not burden the digestive system.

Even at night we have to choose foods that have high nutritional value and avoid or reduce as far as possible by eating healthy foods that are known C”hblni “. Us are eight food groups. In each group the most rich variety. You can choose a meal made ​​up of several groups of food items and you can choose to come from eating the same food.

The following are the recommended food groups by the American Heart Association recommended levels for daily consumption of each group, the person who needs approximately 2000 calories per day. Calories course varies from person to person.

1 Dgnim- this group should consume 7 servings. One serving is defined as 1 slice of bread or ½ cup of cooked cereal.

2 Vegetables should consume five servings. Packet is set to 1 cup leafy life or half a cup of chopped vegetables.

3 cows – recommended 4 servings. Packet is set to 1 medium fruit or ¼ cup dried fruit or ½ cup chopped fresh fruit.

4 Milk and Motzriu- recommended 2 to 3 servings. Packet is set to 1 cup of milk or yogurt or 50 g of cheese.

5 Meat, Poultry and Fish Recommended up to 150 grams per day.

6 nuts, seeds and legumes – 4 to 5 servings per week. Packet is set to 1/3 cup nuts (45 grams) or two

Tablespoons of peanut butter or ½ cup of seeds or dried beans.

7 Oil – recommended 2 to 3 servings per day. 1 serving spoon set tablespoon mayonnaise or oil.

8 sweets and Socr- recommended 5 servings per week. 1 packet is set to 1 tablespoon sugar and ½ cup jam or ice cream

Or a cup of lemonade.

Seemingly, everything is simple. But, not at all. Every group has a “good” and bad. “We have to be smart to know the good guys” and ensure that they are always to be in the kitchen. Their home we do not put bad guys.

Coffee reduces the risk of asthma – a new study states


People who drink coffee on a daily basis and regularly have about a third less asthma symptoms than those who do not drink coffee at all. According to a clinical study conducted at Howard who the United States. Study was conducted on more than 20,000 people, for a number of years. Albeit the two regular coffee, there are a number of reservations in the medical world. Multiple clinical studies that are done on coffee and respiratory diseases, such as asthma, prove otherwise. studies have found that coffee drinking asthma patients who are experiencing an asthma attack, help them breathe easier. There are many doctors in the world, which suggest that coffee drinking urgent first aid for asthma patients who are in an acute attack.

Further research on asthma and coffee, which was held Vskolnd, has shown that drinking two cups of coffee a day, the opening of efficiency and effective airway in cases where a person suffers from asthma attack inhaler (drug) is not within reach.

One of the drugs most widely used in asthma patients is: tincture of theophylline (theophylline).

This drug helps to expand the bronchial tubes, which often inflamed and partially blocking asthma patients. This drug is used for more than 60 years but it is not effective long-term treatment only for acute asthma attacks helps.

In studies found an association between the drug in chemical structure to caffeine and theophylline Therefore, drinking coffee during asthmatic attack nearly as effective as taking the drug theophylline.

Large study in Italy for several years, found that patients with asthma who drink coffee regularly, daily (about 2 cups per day), do not suffer from the symptoms of asthma as asthma patients who do not drink coffee. It was found that the decrease in the symptoms of patients who drink coffee was about 28% compared with those who avoid caffeine